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    RE: Question for Hackwriter
    Lisasnyc posted:
    I recently switched from Avonex to Rebif -as I mentioned in an earlier post- with no adverse effects so far.

    Main reason for this post....
    Hackwriter, has there been any instances of the amount of lesions being reduced/reversed from originally seen on MRI, not due to myelin regeneration, if any?

    I say a discussion on video of 2 doctors on a panel discussing Tysabri and the JCV virus. I though I heard them say something alluding to this, but I could be wrong.

    hackwriter responded:
    Dear Lisasnyc,

    If you're asking whether a disease-modifying drug such as Tysabri can make existing lesions disappear--I've not read anything that makes this claim. Our DMDs are not designed to heal the scars, they are designed to either modify/suppress the immune system and thereby reduce the number of relapses/new lesions, or to introduce molecules that attach themselves to T-cells and "de-fang" them before they attack a myelin protein.

    Hope this addresses your question.

    Lisasnyc replied to hackwriter's response:
    Thanks Kim.

    The doctors were discussing that some patients who are positive for the JCV virus, may still be able to take Tysabri

    The statement that I thought was I heard was that after years on Tysabri, a patient showed a reduction of number of lesions on their follow-up MRI.

    I guess I must of heard wrong because I know you would have indicated if you heard this as well.

    Thanks again.

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