Skip to content

    Announcements

    Exciting News for WebMD Members!

    We've been busy behind the scenes building new message boards for you. You'll have new and easier ways to find messages, connect with others, and share your stories.

    And, this will all be available on your smartphone or other mobile device!

    What Do You Need to Do?

    The message board you're used to will be closing in the coming weeks. While many of your boards will be making the move to our new home, your posts will not. Want to keep a discussion going? Save posts you want to continue (this includes your member profile story), so that you can re-post them in the new message boards.

    Keep an eye here and on your email inbox, we'll be back in touch soon to give you all the information you need!


    Yours in health,
    WebMD Message Boards Management

    LP results
    avatar
    An_253655 posted:
    Hello. I have a rare inflammatory autoimmune disease allied Behcets Disease. I have developed CNS issues so an LP was done. I am confused on my results. If maybe it indicates MS or another type of disease. My Neuro does not think my CNS issues are caused from my Behcets. These are my LP results

    Oligoclonal Ig Bands The patient's CSF contains multiple restriction bands that are also present in the patient's corresponding serum sample. We are unable to define whether these gammaglobulins are of systemic or intracerebral origin.



    Also does anyone know how they determine which Origin the bands are from? Thanks.
    Reply
     
    avatar
    hackwriter responded:
    The results you stated mean that your spinal fluid is not positive for CNS inflammation.

    When testing for MS, a blood sample is also taken along with spinal fluid the day of your LP. A count of o-bands is done on both samples and compared. If the same number of o-bands appear in both samples, it might mean that inflammation that is causing the o-bands in the blood serum could have crossed the blood brain barrier into the CSF.

    If you have a cold virus or some other kind of infection, for example, your blood serum would show bands. Cells that are fighting the infection could then migrate into the CSF and produce o-bands there as well.

    Spinal fluid that is positive for a certain number of bands is a strong indication of MS or some other infection/source of inflammation that is occurring only in the brain or spine. There should be no bands in the blood serum in this case.

    Hope that isn't too confusing.

    Kim


    Featuring Experts

    Stephanie knows multiple sclerosis as a patient and as a nurse. Stephanie was diagnosed with multiple sclerosis in 2013. Shortly after being diagnosed...More

    Helpful Tips

    Tips for Getting Through Cold & Flu SeasonExpert
    The weather is finally cooling down which brings most of us great relief, however flu season is right around the corner! I just wanted to ... More
    Was this Helpful?
    2 of 2 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.