NATIONAL OSTEOPOROSIS FOUNDATION
Jeri Nieves, PhD responded:
Vitamin D can be taken all at one time, with or without food and at any time of the day. Your body stores the vitamin and uses it as needed by the body. It should be fine to take 5,000 International Units (IU) all at one time, as long as this amount was prescribed by your healthcare provider. The upper safe limit of vitamin D was recently set at 4,000 IU/day, however, many times, higher dosages of vitamin D are prescribed for a short period of time to help boost low vitamin D levels. You should take your vitamin D supplement when it is most convenient for you so that you remember to take it.
As for the calcium, you are correct that it should be consumed in amounts of 500-600 at a time or less. NOF recommends a total of 1200 mg of calcium per day from all sources for women age 50 and older. This level is slightly higher than the 1000 mg that is recommended for younger women, due to the impact of menopause.
Individuals should get calcium from foods first and only supplement the approximate amount they do not get from food on a typical day. The combined intake from food and supplements (if needed) should add up to the total amount of calcium you need in one day. If you eat calcium-rich foods like milk, yogurt or calcium-fortified orange juice with your breakfast, it's best to take your calcium supplement with lunch or dinner. If you are able to consume enough calcium-rich foods, you may be able to avoid taking or at least cut back on the amount of calcium supplements you need to take. Getting more calcium than the recommended 1200 mg a day is not beneficial and may cause kidney stones and possibly other problems. To learn more, please read NOF's calcium information at
www.nof.org/aboutosteoporosis/prevention/calcium NOF does not have specific recommendations for taking magnesium and B-12 due to limited evidence supporting the benefits of these supplements to bone health. If your healthcare provider suggested taking these supplements, follow their recommendations for intake. The recommended daily intake of magnesium for you is 320 mg and for vitamin B12 is 2.4 micrograms a day. You can also get many of these vitamins by eating a well-rounded healthy diet rich in fruits, vegetables, low-fat dairy and lean sources of protein.