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Long-Term SSRI Usage-Osteoporosis Link?
kso808 posted:
I am a 57 year-old white male who was diagnosed with severe osteoporosis (particularly in my spine) four years ago. In January 2013, I suffered my first spinal vertebrae wedge compression fracture (T-9), because of an on-the-job injury.

I have been taking SSRI drugs for OCD for over 24 years, and there is increasing evidence that these interfere in the normal bone resorption/rebuilding process, but the jury is still out. There is only scant evidence from studies conducted about this matter, but it is gradually increasing.

Does anyone else fall into the above situation? If so, what is your story?

Take the Poll

For those who have taken SSRI drugs for a long-term period of time, who is now diagnosed with osteoporosis? Particularly interested in male responses.
  • Yes, after 1-5 years of SSRI drug usage
  • Yes, after 6-10 years of SSRI drug usage
  • Yes, after 11-15 years of SSRI drug usage
  • Yes, after 16 years of SSRI drug usage
  • No, even after long-term SSRI usage
View Poll Results
itmatsb responded:
I would like to point out that not being properly treated for depression leads to increased deterioration of telomeres which lead to earlier osteoporosis, stroke, heart disease and cancer. Whether there are safer anti-depressants, I don't know. I just know that I got osteoporosis well before I ever started a different SNRI anti-depressant at age 53. Plus I had a stroke at age 56. I had suffered depression for a number of years before that.

So I might think that not taking anti-depressants could be far worse. Who knows.

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FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

For more information, visit the National Osteoporosis Foundation website