Skip to content
My WebMD Sign In, Sign Up
opiates and brain damage
avatar
leon64 posted:
Large does of opiates over an extended period of time do cause brain damage, especially to the white matter of the brain. This is an area that they have only recently started to study. White matter is critical to brain function and long term use somehow in conjunction with the receptor changes can cause microangiopathy or white matter disease. I believe if your quality of life is improved by taking moderate dosages as directed, it is probably not a great concern. But if your tolerance continually increases and your dose as well, be cautious. Also, inappropriate use tends to make the matter worse. Large dose of oxycodone have recently been implicated in the development of leukoencelopathy, a permanent condition that sneaks up on a person taking large doses for extended periods of time. We just don't know at what level things become toxic. It varies from person to person and depends on their overall health, other meds they take, and other medical conditions they may have.
Reply
 
avatar
annette030 responded:
Where did you get this information? I would like to read the studies myself, if you have links...
 
avatar
blessedladyptl responded:
Please post the link to your source.


Featuring Experts

David N. Maine, MD is the director of the Center for Interventional Pain Medicine at Mercy Medical Center in Baltimore. Maine graduated with a degree ...More

Helpful Tips

want to know if anyone has gone threw the pain im having
got a bulgin disc between c5 c6 pain goes form my neck all down my spain threw my back... the lower part of my back is swollen.... have ... More
Was this Helpful?
2 of 13 found this helpful

Related News

There was an error with this newsfeed

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.