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    Not Immune to MMR, even though had Mumps & MMR Vaccine
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    Anon_170430 posted:
    I am so confused. My pediatrician's office has been closed for years. I am returning to school full-time for my MBA and thus must show proof of MMR vaccination or immunity. Since I do not have my vaccination records, I just had MMR titers. Results came in: I have no immunity to measles, mumps or rubella? And, to make things even stranger, me and all 5 of my brothers as children contracted mumps. How can this be? I was born in 1969, and NJ requires all children to be vaccinated before entering school. And I know I was vaccinated against all because I remember my mom's old vaccination records for me and my brothers listing all of our vaccinations and when we were vaccinated. What makes me nervous is that me and all of my brothers had the MMR vaccine, yet still got the mumps. Even scarier, I'm showing no immunity of to Mumps even after the mumps and the MMR vaccine. Is this even possible??
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    njvegetarian responded:
    Forgot to add above to my MMR post: is it possible that the vaccine doesn't work in my family? Is it possible that mine - and my brothers' - children and future children may not be able to develop an immunity to MMR. Should my brothers' and all of our children receive MMR titer testing to see if it's not just me who hasn't developed an immunity?
     
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    Roy Benaroch, MD replied to njvegetarian's response:
    About 15% of people do not develop antibody titers to one or more of the components of MMR after a single dose. After two doses, about 2% will still not have positive titers. Though that doesn't sound very high, in a busy city with a lot of people, it means there is a significant quantity of people who are not immune. That's why it's so important for everyone to get these vaccines-- it not only protects you, but it protects the people who don't respond to the vaccine, plus the people too young to get the vaccine, plus the people who for medical reasons can't be safely vaccinated.

    For many years, rates of vaccination were so high that Measles, Mumps, and Rubella were essentially unseen in the United States and most of the developed world. Thanks to the lies and fear-mongering of the antivaccine crowd, the world is no longer as safe even for those of us who are vaccinated.

    After natural infection, most (but not all) people develop high antibody titers to these diseases. But even natural infection isn't 100% protective.

    Non-reactions to vaccines do not run in families. There really isn't any reason to test other people in your family for these titers. Instead, make sure that you and your family receive TWO documented doses of MMR. It may be that you never got that vaccine as a child, or that a different product (not containing all 3) was used, or that it was stored improperly, or that you are one of the unlucky ones who won't respond to this vaccine.

    Best of luck!
     
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    njvegetarian replied to Roy Benaroch, MD's response:
    Thanks, Dr. Benaroch! This is very helpful. Regarding my family, though, the reason I was thinking that at least my brothers should get checked is because we all were innoculated with MMR at different times because we are years apart from one another. Yet, we all got the mumps in 1977. The 2nd to youngest brother got it from a classmate and then we all got it from our brother. I can see a faulty batch if we all were innoculated at the same time, but we were all innoculated as required to enter school. Also, me and my 2nd to youngest brother had the same pediatrician, but our 3 oldest brothers were vaccinated had a different pediatrician in a different part of the state. It's just seems so strange.
     
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    Safflowerchick replied to Roy Benaroch, MD's response:
    I have had this shot 4 times now, and I still have NO antibodies.. any clue why??
     
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    ashley128 replied to Roy Benaroch, MD's response:
    I have had this vaccine 5 times. And it still does not appear on titer. My mom, sister, grandmother, and my 7 year old son are the same (my mom actually had the mumps as well). Any time our blood is drawn and they do a full blood test they come back and say we have never had the mmr vaccine. I always thought it was genetic.
     
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    kathesue replied to ashley128's response:
    That is very interesting! I wonder how many vaccinated people don't actually have titers--and therefore, do not have immunity.
     
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    labcitygurl responded:
    I am one of those that the vaccine does not work for. I had my babies in my 20's and before each one (there's 4 of them) my blood test results would come back not immune to rubella. So I would get a vaccine. I had three in a period of 4 years and I am still not immune. And now I have Rheumatoid Arthritis which I believe is because of all the vaccines. I looked at the label for the mmr vaccine and arthritis is one of the side effects of the drug. I would caution anyone getting this vaccine to do your research first.
     
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    stormysky responded:
    I've had the rubella vaccine 4 separate times and I too do not have titers. I've found out after having this vaccine multiple times that I in fact have a genetic disorder that I've passed on to my children. The name of this disease is CVID (Common Variable Immune Deficiency). This disease can be genetic, which in my case is. I would recommend all of you to see an immunologist and have testing for this disease. I do weekly infusions of subqutaneous IG, so I basically get antibodies from donors. I have arthritis and I've always had that gut feeling the rubella vaccine caused this just like I had a gut feeling not producing antibodies after sever injections of this vaccine was not right. Trust your instincts many doctors tried to tell me nothing was wrong and there was nothing to worry about, they were very wrong had I been given a simple blood test they would have gotten answers and I wouldn't have ended up in the hospital with swelling in my brain and blood clots from a picc line that eventually lead to my diagnosis.
     
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    stormysky responded:
    I've had the rubella vaccine 4 separate times and I too do not have titers. I've found out after having this vaccine multiple times that I in fact have a genetic disorder that I've passed on to my children. The name of this disease is CVID (Common Variable Immune Deficiency). This disease can be genetic, which in my case is. I would recommend all of you to see an immunologist and have testing for this disease. I do weekly infusions of subqutaneous IG, so I basically get antibodies from donors. I have arthritis and I've always had that gut feeling the rubella vaccine caused this just like I had a gut feeling not producing antibodies after sever injections of this vaccine was not right. Trust your instincts many doctors tried to tell me nothing was wrong and there was nothing to worry about, they were very wrong had I been given a simple blood test they would have gotten answers and I wouldn't have ended up in the hospital with swelling in my brain and blood clots from a picc line that eventually lead to my diagnosis.
     
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    mitasize responded:
    When my daughter was 3 she went to a pediatric oncologist because she was always sick and was unable to fight infection. After a battery of tests they found that none of the immunizations she had in her first 3 years of life were in her system. Not a single one. They ended up redosing all of those immunizations. Soon after she started being able to fight infection and was no longer constantly sick. Within a couple months of being revaccinated we noticed she was different. She went from sleeping 10 hours a night to sleeping about 2 hours. Went from 2 naps a day to none. She was very fussy, irritable, started having daily physically violent tantrums and suddenly unable to get along with other children. She became a danger to herself and others. My once quiet, perfect child became a child that I couldn't handle. She had a difficult time in all grades of elementary. She was kicked out Of 3 daycares, 2 public schools and a private school and this was all before 3rd grade. We saw countless different physicians, neurologists, psychologists, psychiatrists, etc. Nobody seemed to believe me when I would tell them that she would go into a sudden 2 hour rage, hitting her head violently onto the tile floor until it would bleed, throw kitchen chairs and any items she could grab, would punch and kick wall's and people. You could look into her eyes during these rages and tell that she "wasn't there". In the blink of an eye they would stop. I'm covered in bruises, as is she, and She would say she was going to go eat an Apple like nothing had happened. The hardest day I ever had was when she was 8. She went into a horrible rage as she did daily but this time she was trying to strangle herself. The hardest decision I ever made was right then when I decided to video tape her instead of stop her. I spent 5 years trying to convince doctors she had a problem and this time I got it on tape. I brought her and the video into a psychiatric hospital. Initially they said she was fine and just go home........until they saw the tape. They admitted her into the pediatric psychiatric ward. She was there for 3 weeks. The first few days she was in restraints due to her rages. After that she was always on a 1:1 (1 staff with her 24/7) . It was then that I finally found a doctor who believed me. My daughter is almost 12 now. She has been through years of different medications. Her body metabolizes the meds so fast that only trace amounts are ever found in her blood. She has been diagnosed with autism and severe bipolar disorder. Her Dr still says he has never seen a child this severe before. I am a mom of 4 kids, a registered nurse and a wife. I believe in getting vaccinated........ But I can't help but think that it was the revaccination when she was 3 years old that caused this. If I had to do it all again I would still have revaccinated her, but I would have spread the vaccines out over a period of time instead of doing them all at once as the doctors recommended.
     
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    An_267330 responded:
    My wife's entire family, and now my daughter have contracted Measles despite being vaccinated. Since my daughter is 6, she was vaccinated twice, which is the current CDC guidance to obtain 99% efficacy. Even with the lower 95% effectiveness of a single MMR vaccine, the odds of my wife, her sister, her brother, her mother and my daughter all getting Measles with 5% odds each is 1 in 1 million. Therefore, there certainly seems to be inherited resistance to the vaccine, at least for Measles. When we asked her doctor about this hereditary link to vaccine resistance, they just sort of avoided the question -- like politely not wanting to say we are crazy despite the overwhelming correlation in our case.


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