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cause for Parkinson's Disease

An_246761 posted:

My husband was diagnosed over 9 years ago with Parkinsons Disease. Years earlier, he was given a cadaver bone in his neck. Is it possible that the dna from the bone had Parkinson's in it? No one in his family has ever had Parkinson's Disease. He has two brothers and neither have symptoms either.

1 Replies |Watch This Discussion | Report This| Share this:cause for Parkinson's DiseaseMy husband was diagnosed over 9 years ago with Parkinsons Disease. Years earlier, he was given a cadaver bone in his neck. Is it possible that the dna from the bone had Parkinson's in it? No one in his family has ever had Parkinson's Disease. He has two brothers and neither have symptoms either.

DUKE MEDICINE

Mark A Stacy, MD responded:

Dear An_24671
Thank you for your note. I am not sure we could ever know if the cadaver transplant could be a trigger for PD, but most of the time, this disorder would not affect multiple family members. I had never really thought about PD risk and transplant. With transplant of functioning organs - like heart, lung, kidney - there are live cells, so maybe. However, the PD symptoms seen in these cases is usually from medications for nausea.

A cadaver graft would not be likely to have live cells, so it is most unlikely.

Report This| Share this:cause for Parkinson's DiseaseDear An_24671<br />Thank you for your note. I am not sure we could ever know if the cadaver transplant could be a trigger for PD, but most of the time, this disorder would not affect multiple family members. I had never really thought about PD risk and transplant. With transplant of functioning organs - like heart, lung, kidney - there are live cells, so maybe. However, the PD symptoms seen in these cases is usually from medications for nausea. <br /><br />A cadaver graft would not be likely to have live cells, so it is most unlikely.

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