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worn1 posted:
Dr Stacy
When they do bone marrow transplants they are checking for compatibillity. Do they perform testing for gene abnormalities such as parkinsons if parkinsons runs in the donors family? I never gave it much thought until the question on transplants.

Also concerning dyes in medication is there one type of dye that causes reactions more than the others. I know they use different products to produce color varience such as different shades of yellow dye which explains why some cause reactions and some do not.

w
1 Replies |Watch This Discussion | Report This| Share this:transplantDr Stacy<br />When they do bone marrow transplants they are checking for compatibillity. Do they perform testing for gene abnormalities such as parkinsons if parkinsons runs in the donors family? I never gave it much thought until the question on transplants.<br /> <br />Also concerning dyes in medication is there one type of dye that causes reactions more than the others. I know they use different products to produce color varience such as different shades of yellow dye which explains why some cause reactions and some do not.<br /> <br />w
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DUKE MEDICINE
Mark A Stacy, MD responded:
I had not thought about that either! Cadaver grafts are not genotyped (or checked for genetic risk factors), and organs are evaluated for the potential of donor rejection.

I do not know why the yellow dye causes a rash - but it is the most commonly prescribed type of levodopa, and maybe the other dyes can (rarely) cause this too.
Report This| Share this:transplantI had not thought about that either! Cadaver grafts are not genotyped (or checked for genetic risk factors), and organs are evaluated for the potential of donor rejection.<br /><br />I do not know why the yellow dye causes a rash - but it is the most commonly prescribed type of levodopa, and maybe the other dyes can (rarely) cause this too.
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