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Nicotine and PD II
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sparky1109 posted:
I recently wrote you about my experience having started smoking eight years after being diagnosed with PD. I did not mean to say that I found it a complete help. I have noticed a sudden and sometimes almost complete inability to move after smoking a cigarette. Nicotine is supposed to increase the dopamine released to the brain, it seems to be having the opposite effect on me, while (at the same time)relieving 'sluggeish bowel syndrome' somewhat. I am cutting down on the smoking as the immobility spells seem to be worsening.
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Mark A Stacy, MD responded:
Hi, sparky 1109
I think your experience with mobility after nicotine is more consistent with the nicotine patch trials in the 1990's. There is some effort to study a nicotine like drug for dyskinesias, but do not know the current plans for this effort. I would agree with stopping tobacco use.


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