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    reprogramming of astrocytes
    avatar
    worn1 posted:
    Dr Stacy
    I just read an article in science daily concerning the reprogramming of astorcytes to produce dopamine. It produced more questions than it answered, Assuming this works what would stop the same destruction of the reprogramed astorcytes that is happeining to the neurons producing dopamine?


    w
    I know its experimental--many years down the road and any answer you give would be a guess.
    Reply
     
    avatar
    DUKE MEDICINE
    Mark A Stacy, MD responded:
    Hi, worn1
    I do not know of this work. I think it is an interesting idea for dopamine delivery. Would be concerned about how to target the astrocytes in the striatum (to help PD) vs the cortex (and cause symptoms of schizophrenia. (The brain is like real estate - location, location, location.)
     
    avatar
    worn1 replied to Mark A Stacy, MD's response:
    Dr Stacy
    Here is the web site (hopefully--I am lousy with relaying websites)
    www.sciencedaily.com

    w
     
    avatar
    worn1 replied to worn1's response:
    it worked. type in astrocyte in the search box. about half way down the page.

    dec of 2011
    there are also a couple of current articles on this same page

    w
     
    avatar
    worn1 replied to Mark A Stacy, MD's response:
    Perelman School of Medicine located at the University of Pensylvannia performed the research. The aritcle appeared in Science Daily 13 Dec 2011. I can find information but getting to other people has always been a problem. At work I just print it off and deliver it to who ever requested the info.

    w
     
    avatar
    susiemargaret replied to worn1's response:
    hello, all --

    the astrocytes article is at http://www.sciencedaily.com/releases/2011/12/111213144721.htm .

    i know there has to be a way to get the dec 13, 2011, front page, so that you can look at the other "current articles" on the same page (see fourth post above), but i can't figure it out. sorry!

    -- susie margaret
    what good is gold, or silver too, if your heart's not good and true -- hank williams, sr.
     
    avatar
    worn1 replied to susiemargaret's response:
    Thank You susiemargaret

    http://www.sciencedailey.com/release/2012/04/120425115314.htm .

    http://www.sciencedailey.com/release/2012/04/120417143855.htm .

    There is also an article published by Reuters in Science Daily Titled
    Scientists "switch off" brain cell death in mice
    I was unable to figure out how to get the link for this article
    London May 6 2012 (Reuters)

    w
     
     
    avatar
    susiemargaret replied to worn1's response:
    hello, W --

    the "brain cell death" article is at http://www.newsdaily.com/stories/bre84509x-us-brain-neurodegeneration . it is in news daily, not science daily, but they look like they are published by the same people.

    -- susie margaret
    what good is gold, or silver too, if your heart's not good and true -- hank williams, sr.
     
    avatar
    worn1 replied to susiemargaret's response:
    Thanks again susie margaret!!
    I hope these arrticles give hope.
    Just think maybe this is part of the solution for all neurological disorders
    This article gives me hope that they will be able to stop the domino(SP) destruction of our brain cells.combine this with astrocytes taking over dopamine production we would not have to worry about further loss of movement and memory. Eventually No one would have to experience Parkinsons, Alszheimers, MS etc.

    w

    I


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