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    Have Parkinson's Disease and get leg pain 4 to 5 times daily
    An_245699 posted:
    My wife is 80 years of age and has Parkinson's Disease since 2006.

    She has for some time now getting severe pains in the upper and

    lower parts of her legs. She takes Sinemet 25/100 4 to 6 times daily.

    When she has "On Time" no pain; 1/2 to 1 hour prior to taking the

    Sinemet she starts to get pain and 1/2 to 2 hours it takes to get back

    to the "On Time" that is when the pain leaves her. We have tried

    taking the Sinemet at different times and different doses, with no

    help. Does anyone have any suggestions?
    worn1 responded:
    I'm sure Dr Stacy will correct the information if I am wrong.
    It sounds like it is time to contact your neurologist and let him/her know what is happening. Your neurologist may prescribe a dopamine agonist such as requip or mirapex.
    sparky1109 responded:
    I am not a nuerologist but as a result of my experience of almost nine years of suffering with this disease I cannot urge you more to avoid adding a dopamine agonist to your wife's medications. The lag time that occurs between taking the medication and its effect is most probably caused by what is referred to as 'sluggish bowel syndrome'. Parkinson's affects the ability to digest food and in an 80 year old woman I don't imagine that she gets the kind of exercise that would help with that. You should keep her on a low protien diet (plenty of veggies and whole grains) and take the sinemet just before meals.

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