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MTHFR and Factor V: Scared to try again!
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dischm1 posted:
Hi All,
I was diagnosed with hetero Factor V and heterozygous for the C677T mutation in the MTHFR gene after our second miscarriage. We have had a total of four now and I'm so scared to try again until we make sure we have all our ducks in a row to the best of our ability. With the 3rd and 4th pregnancy, I was put on Lovenox early on, but now I'm being told I should start at ovulation next time.

I feels like all the focus has been on Factor V and the more I read about MTHFR, I'm almost more worried about that being the cause. It sounds like due to the MTHFR mutation I am unable to absorb folic acid like others and to be on Folate (as Metafolin) in order for my body to get what it requires. Since folic acid is a key component in preventing neural tube defects, I can't help thinking this is a huge factor in my miscarriages yet none of my doctors or specialists have ever mentioned this aspect.

I'm wondering if any of you are going thru the same concerns? Have found good information on this topic? Mostly your feelings on this and what you did if you are in this same boat!?

Thanks in advance for any help or information!
0 Replies |Watch This Discussion | Report This| Share this:MTHFR and Factor V: Scared to try again!Hi All, <br />I was diagnosed with hetero Factor V and heterozygous for the C677T mutation in the MTHFR gene after our second miscarriage. We have had a total of four now and I'm so scared to try again until we make sure we have all our ducks in a row to the best of our ability. With the 3rd and 4th pregnancy, I was put on Lovenox early on, but now I'm being told I should start at ovulation next time. <br /><br />I feels like all the focus has been on Factor V and the more I read about MTHFR, I'm almost more worried about that being the cause. It sounds like due to the MTHFR mutation I am unable to absorb folic acid like others and to be on Folate (as Metafolin) in order for my body to get what it requires. Since folic acid is a key component in preventing neural tube defects, I can't help thinking this is a huge factor in my miscarriages yet none of my doctors or specialists have ever mentioned this aspect. <br /><br />I'm wondering if any of you are going thru the same concerns? Have found good information on this topic? Mostly your feelings on this and what you did if you are in this same boat!? <br /><br />Thanks in advance for any help or information!
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