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I've done a lot of research trying to find a connection to altitude and RA, and have found virtually nothing. Even the Arthritis Foundation in Denver found no studies or definitive info.
I have RA (18 yrs now) w/several other associated issues(Sjogren's Syndrome, Fibromyalgia, RLS, Raynaud's and Hyperthyroid) I live in Wisconsin and have visited Colorado, Nevada and Palm Springs CA several times - I always feel better in thoses states! Esp Nevada no pain at all.
I personaly think it has more to do with the barametric pressure than altitude. Our pressure can change hourly in WI and the humidity is killer - I have tracked the weather and how I feel (what hurts and how much), can say it definalty has to do with changing pressure for me.
My friends come see me to find out when the weathers going to change (they gage it by how badly I feel) - it's kinda of fun to see if I predict the weather correctly, sometimes it's better than our local weather people. LOL
Take care - be well.

I too have RA and have had it now for 15 years. My last rheumatologist made a passing comment not long ago when I was having a bad period. He said, "You might consider moving to lower altitude". I did not think much of it because moving is not an option. I am now curious about it and why he said it. I have lived a 9000 feet and had zero issues, run to the top of Pikes Peak with no issues, climbed in the Himalaya and had no issues and have lived in the same place at 9000 and have had HUGE issues. So for me it is hard to say. I would be happy to round up funding if someone else can manage the study - I don't have the bandwidth to be a primary coordinator right now. I am a grant writer and live just outside the Denver Metro area at about 6500 feet now. I do believe that a lower humidity place seems beneficial. I don't know why and I understand the etiology of the disease fairly well. I wonder if the higher altitude negative impacts might be this. Our blood is often filled with antibodies (more than most), when at higher altitude our blood also thickens as a result of more hemoglobin. The two together would thicken the blood which then affects the circulation of oxygen and causes hypoxia. This can cause all sorts of "bad" feelings -- lethargy, muscle pain due tp low oxygen levels etc. Do you think there is anything to this? Couple that with the lower barometric pressure and it can add up to a flare. At the same time when folks talk about feeling BETTER at high altitude they might be able to attribute that to lower humidity. The crux of this disease is that it is so different in every sufferer and there are so many variables that it is challenging to study unless you virtually eliminate external variables. The internal ones, genes, attitude, pain tolerance, etc. are impossible to eliminate!
I live in the San Francisco Bay Area -- relatively dry, and quite at sea level. Just went over the long MLK weekend for a skiing trip to Lake Tahoe, for the first time since the RA diagnosis, where we were staying at about 5k feet and spending the days going up and down between there and 10k feet of elevation. Had a huge flare up -- worst pain (especially in my feet) I've had. And no, not from the impact of the snowboarding and its requisite boots . . . the situation worsened overnight each night, after 14 hours of rest from the board/boots, and it was as bad in my hands (unused in boarding, once you figure it out) as it was in my feet. By the third day there I was wondering if this is the end of skiing/boarding for me, which would be a bummer.
With just 24 hours back at sea level today, everything's back to normal. Not even any pain from the 15-mile fast bicycle commute to work this a.m. Go figure.
Steven
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