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    Methotrexate side effects
    avatar
    Gwendolyn123 posted:
    Has anyone noticed that irritability is a side effect of taking this med. I was on 7 pills weekly and my family all say that I am very irritable and even mean at times while taking this med.
    Reply
     
    avatar
    lcover responded:
    Hi Gwendolyn,

    Yes, I experienced that, severe depression and anxiety while taking methotrexate. I was amazed at how it effected me and my mood/behavior.

    I believe my doctor decreased the dosage and had me take folic acid to help with all of the side effects I was experiencing. Eventually, I had to stop taking it because it gave me a lung infection. I have heard it works great for most people, unfortunately I was not one of them!

    Hope you get the information you need.

    Take care,
    LC


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