Skip to content

    Announcements

    Exciting News for WebMD Members!

    We've been busy behind the scenes building new message boards for you. You'll have new and easier ways to find messages, connect with others, and share your stories.

    And, this will all be available on your smartphone or other mobile device!

    What Do You Need to Do?

    The message board you're used to will be closing in the coming weeks. While many of your boards will be making the move to our new home, your posts will not. Want to keep a discussion going? Save posts you want to continue (this includes your member profile story), so that you can re-post them in the new message boards.

    Keep an eye here and on your email inbox, we'll be back in touch soon to give you all the information you need!


    Yours in health,
    WebMD Message Boards Management

    Includes Expert Content
    Stopping and restarting Actemera?
    avatar
    An_246664 posted:
    I was taking actemera for about a year and a half and I absolutely loved it, my arthritis was better than ever. About three months ago I had to stop the infusions because of an infection in my gums, I will be having oral surgery soon, so should be able to get back on the drug once I am cleared of infection. However I am planning to try and get pregnant in about 9 months, so I would get off of the acetemera again for that. I have heard that when taking a hiatus from meds like this you run the risk of the medicine not working or not working as well once you go back on it.... is this true???? Should I wait until after the possible future pregnancy to get back on acetemera, or is it okay to take two hiatuses from this medicine within one year?

    Any information would be greatly appreciated!
    Reply
     
    avatar
    Scott Zashin, MD responded:
    Yes, you are correct that it is possible althought not common that after stopping and then resuming an RA drug after a prolonged time may subject you to the possibility that you will not recapture the same benefit. In addition,with some medications such as Remicade, there is also a higher risk of infusion reactions after a period of time of discontinuation as antibodies develop.Remicade is made from mouse protein so it is a foreign proteinto the body. I don't know if there is a higher chance of reactions or risk of decreased efficacy with Actemra re starts as I have just started using it in my patients. I would talk with your doctor to see what he feels is best for you in terms of timing of your pregnancy and medications.I do not know if stopping twice is any more likely to have an effect on efficacy than stopping once. Glad Actemra has helped! A recent study showed it was more effective than Humira when each drug was given by itself.


    Helpful Tips

    help with methotrexate side effectsExpert
    I recommend all my patients on methotrexate take at least 1 mg of Folic Acid daily to help decrease the risk of side effects. In those ... More
    Was this Helpful?
    30 of 33 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.