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Help! In denial....Seronegative RA?
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hobnob56 posted:
Hi all,
I am 47 and have been having stiffness and pain for at least 2 years. It started in my feet and ankles, and now is pretty generalized. I am also fatigued most of the time. My RA factor is negative. ESR is consistent in the 30's and CRP is 13. (not 1.3) I currently am on Celebrex daily and if I miss a day, boy do I feel it!. My Dr. wants me to start methotrexate but I am afraid to start. Also, maybe if RA was positive I would be more at peace with the diagnosis?

I have had frequent tendon issues and have some tears in my right wrist. Not sure if that is from RA (Inflammatory Arthritis). Not bad enough for surgery. I am trying to do an exercise program but my joints are screaming!! Should I be doing vigorous exercise/ weight training?

I guess I am just looking for some advise, maybe a kick in the pants?!

Help!
Reply
 
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Scott Zashin, MD responded:
Some other tests I would check on a patient who gave me that history is a CCP(another RA test) and an HLA B27 gene to look for a different type of arthritis. A positive gene test can be found in 8 % of the population so a positive test is not diagnostic. I will use MTX in the 15-20% of my patients with RA who are seronegative (no RF) if they have swelling and high measures of inflammation to help symptoms and decrease the risk of damage, deformity and disability.
 
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hobnob56 replied to Scott Zashin, MD's response:


Thank you for your reply. My doc did those and more and all are negative except for CRP, ESR and Homocysteine. I did get the Rx filled.....Still haven't made the comittment to start. Is it "normal" for someone to have tendon/ligament issues as a main symptom of this? I have had tendonitis in multiple joints and am not really that athletic!.. Never played tennis but got tennis elbow. (lol)

Thanks again.
 
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Scott Zashin, MD replied to hobnob56's response:
The tendons may be involved in RA also.I have not heard of the ligaments being affected.(tendons attach muscle to bone and liagaments attach bone to bone)


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