Skip to content

    Announcements

    Exciting News for WebMD Members!

    We've been busy behind the scenes building new message boards for you. You'll have new and easier ways to find messages, connect with others, and share your stories.

    And, this will all be available on your smartphone or other mobile device!

    What Do You Need to Do?

    The message board you're used to will be closing in the coming weeks. While many of your boards will be making the move to our new home, your posts will not. Want to keep a discussion going? Save posts you want to continue (this includes your member profile story), so that you can re-post them in the new message boards.

    Keep an eye here and on your email inbox, we'll be back in touch soon to give you all the information you need!


    Yours in health,
    WebMD Message Boards Management

    Includes Expert Content
    Need info on biologics
    avatar
    olathegal posted:
    My Dr is considering biologics for better control of RA. I've been on methotrexate weekly injections for a year. She has increased the amount slowly throughout the year. Also prednosone injections every 3 months. We've determined I need to look at other options and biologics is the next step. I would appreciate your feedback on what you have found successful. thanks
    Reply
     
    avatar
    Scott Zashin, MD responded:
    For the majority of my patients, I will use the TNF blockers Humira or Enbrel as my first biologic because patients can give it themselves at home and don't need to go to a clinic to get an as with Remicade. .I have the most experience with these two,(your insurance may dictate which they will pay for) You may enjoy reading my book, Arthritis without Pain. It was written a while back but it still has useful information about the TNF blockers. Newer TNF's that are now available include Cimzia and Simponi. They may be less likely to cause a burning sensation which may occur with the earlier released injections. Orencia is a different class of biologics that may be used as a first line drug. When adding a biologic, I will typically continue the MTX as up to 80 % of patients need combination therapy with a DMARD like MTX to achieve an optimal response.


    Helpful Tips

    help with methotrexate side effectsExpert
    I recommend all my patients on methotrexate take at least 1 mg of Folic Acid daily to help decrease the risk of side effects. In those ... More
    Was this Helpful?
    30 of 33 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.