Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Includes Expert Content
WebMD Article: Preventing Joing Damage (Need some clarification)
lcover posted:
There is a WebMD article called Preventing Joint Damage From Rheumatoid Arthritis. The article mentions three things that I was hoping to get clarification on.

1. It says "You can also have low levels of disease activity that come and go without your feeling any symptoms." I'm assuming this is prior to getting treatment. Can this happen while taking biologic meds?

2. It also says "This is called degenerative disease, and it is similar to what happens in "regular" or "wear and tear" arthritis (osteoarthritis ) -- only it happens faster in people with rheumatoid arthritis." I'm looking for clarification on the last sentence. Can OA happen faster with people who have RA?

3. Under treatment it states "Get treated early. Much of the joint damage that eventually becomes serious starts soon after rheumatoid arthritis is discovered. " Why is this?

I appreciate any information.


Scott Zashin, MD responded:
Early diagosis of RA and treatment can help prevent damage, deformity and disability. Damage may occur as early as 6-12 months. Patients with RA due to chronic inflamamation are more likely to get secondary OA. This does not happen quickly and occurs over years.Finally, patients on biologics can get joint damage without symptoms if they have peristent joint swelling.I don't worry about this if I I have a patient on a biologic who has no pain or swelling and has a normal ESR and CRP. (blood tests for inflammation)

Helpful Tips

help with methotrexate side effectsExpert
I recommend all my patients on methotrexate take at least 1 mg of Folic Acid daily to help decrease the risk of side effects. In those ... More
Was this Helpful?
30 of 33 found this helpful

Related Drug Reviews

  • Drug Name User Reviews

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.