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    court112410 posted:
    so im 20 years old bout to turn 21 i have reiters syndrome/reactive arthritis and rheumatoid arthritis i jus now started methotrexate about one hr ago, im jus sitting here terrified about the side effects that may are may not happen can someone plz tell me what to expect...... sincerly courtney
    allie_bf responded:
    It will take a few weeks for symptoms to develop. When I started MTX, I also thought I might have a tough weekend right off the bat, but it didn't happen that way. The doses for arthritis are a lot lower than the doses for cancer so we don't get the severe side effects that cancer patients get with this drug; still, it's important to be aware of the potential side effects. The biggest thing that I've seen is a loss of appetite, especially on days #2 and 3 after I take my weekly dose.
    xperky responded:
    I worry every time I take a new medicine too. Mostly, you are watching for any allergic reaction in the first few hours, and that's unlikely.

    I get more aches and tiredness about 12 hours through 36 hours after taking my dose. I plan an easier activity level for 2 to 3 days each week. Then, on day 4, I get a boost of energy! I guess it's from the medicine, but it could only be because I didn't push myself for a while.

    Good luck on the mtx. I hope you feel better after a few weeks.

    Helpful Tips

    help with methotrexate side effectsExpert
    I recommend all my patients on methotrexate take at least 1 mg of Folic Acid daily to help decrease the risk of side effects. In those ... More
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