Skip to content
Chancre developed after penicillin treatment
louphoenix posted:
I was exposed to STDs due to a terrible decision making night on April 5. After a night of drinking way, way too much, I performed unprotected penetrative oral and anal sex on another male who I had just met that night. I am uncircumcised and I am aware that it increases the risk of acquiring HIV. The next day I woke up with my senses back on, freaked out and ran out to the hospital, where was given an STD risk assessment and received a course of antibiotics (for chlamydia and gonorrhea), a penicillin shot for syphilis and a prescription for nPEP in case of HIV exposure (which I'm still taking until May 3 for a total of 28 days). I should also note that my baseline status is clean. I have had only 1 monogamous (female) partner during the past 5 years and I was screened and tested squeaky clean about 1 1/2 years ago.
One of my immediate concerns and the point of this post is that several days after the penicillin shot, a chancre appeared on the shaft of my penis. I should note that the sore matches a syphilis chancre to a T: single, painless, round sore with some discharge (it no longer leaks but the chancre is still there). It also looks a lot like most of the syphilis chancre images I've seen on Google.
Does the presence of a chancre after treatment imply that the penicillin shot did not work as intended? or could it be that treatment requires a period of time to work where primary syphilis symptoms could still manifest while the antibiotic takes effect? It's been 17 days since I received the penicillin shot. I will have a follow up visit with my primary doctor next week, but I wanted to ask and find out if it's even possible for a chancre to appear after being treated less than 24 hours after exposure.
georgiagail responded:
Since you have an appointment with your physician next week, you can show him what you consider a chancre and discuss whether this indicates syphilis.

louphoenix replied to georgiagail's response:
I definitely will. I just want to know now if that's even possible after treatment. Is it?
louphoenix responded:
louphoenix responded:
any opinions on this? ...anyone?

Helpful Tips

how do you feel towards the ONE WHO GAVE YOU HERPES
Did you know that 90% of people living with Herpes, DON'T KNOW THEY HAVE IT . Thats a big number. So you just found out you have Herpes, ... More
Was this Helpful?
42 of 53 found this helpful

Related Drug Reviews

  • Drug Name User Reviews

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.