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    Chancre developed after penicillin treatment
    louphoenix posted:
    I was exposed to STDs due to a terrible decision making night on April 5. After a night of drinking way, way too much, I performed unprotected penetrative oral and anal sex on another male who I had just met that night. I am uncircumcised and I am aware that it increases the risk of acquiring HIV. The next day I woke up with my senses back on, freaked out and ran out to the hospital, where was given an STD risk assessment and received a course of antibiotics (for chlamydia and gonorrhea), a penicillin shot for syphilis and a prescription for nPEP in case of HIV exposure (which I'm still taking until May 3 for a total of 28 days). I should also note that my baseline status is clean. I have had only 1 monogamous (female) partner during the past 5 years and I was screened and tested squeaky clean about 1 1/2 years ago.
    One of my immediate concerns and the point of this post is that several days after the penicillin shot, a chancre appeared on the shaft of my penis. I should note that the sore matches a syphilis chancre to a T: single, painless, round sore with some discharge (it no longer leaks but the chancre is still there). It also looks a lot like most of the syphilis chancre images I've seen on Google.
    Does the presence of a chancre after treatment imply that the penicillin shot did not work as intended? or could it be that treatment requires a period of time to work where primary syphilis symptoms could still manifest while the antibiotic takes effect? It's been 17 days since I received the penicillin shot. I will have a follow up visit with my primary doctor next week, but I wanted to ask and find out if it's even possible for a chancre to appear after being treated less than 24 hours after exposure.
    georgiagail responded:
    Since you have an appointment with your physician next week, you can show him what you consider a chancre and discuss whether this indicates syphilis.

    louphoenix replied to georgiagail's response:
    I definitely will. I just want to know now if that's even possible after treatment. Is it?
    louphoenix responded:
    louphoenix responded:
    any opinions on this? ...anyone?

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