I've learned to live with this, but would love to learn of a cure. My dermatologist suggested a urea-based cream, Flexitol, that does soften the skin, but if I stop using the cream, the scaly skin returns within less than a week.
On many backpacking trips in the 1970s, I shared socks with a colleague who had this condition and I'm pretty sure I must have picked it up from him. He said it was a fungus he had developed in a Philippine jungle.
I've tried ALL of the over-the-counter treatments for athlete's foot, but nothing permanently makes this condition go away. I've had athlete's foot and this really is different--no itching or burning, only terribly dry, thick, cracked skin--and only on the knuckles of the big toes, no other toes and nowhere else on my body.
Just letting you know that you're not alone, I have the exact same problem. I've never been exposed to anything like a jungle fungus so I doubt that is the cause, however. Thanks for saying that Flexitol helps, I haven't found anything that can make it go away so far so i'm going to give it a try.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
The opinions expressed in WebMD Communities are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. Communities are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatments or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment.
Do not consider Communities as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.