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One of the most interesting studies was presented in a poster by Dr Andrea Vansickel and colleagues at Professor Tom Eissenberg's laboratory at Virginia Commonwealth University. This group had previously published a study of e-cigarette use in cigarette smokers which found that they obtained only negligible levels of blood nicotine from the e-cigarettes. In the poster last week they reported preliminary results from the first 3 subjects in a new study of regular e-cigarette users. Each of these e-cigarette users used their own modified e-cigarettes and at least two of them obtained significant increases in blood nicotine concentrations, reaching more than 10 ng/ml from 10 puffs over 5-minutes, and one reached over 30 ng/ml with continued use. These levels are comparable to the venous blood nicotine levels that can be absorbed by a cigarette, and I believe this is the first time this has ever been reported. I am looking forward to reading the full results when the study is completed and published in a peer-reviewed journal.
These preliminary findings raise some interesting issues and questions. Is it the specific characteristics of the devices used by the participants in this study that enable them to absorb significant amounts of nicotine, whereas other devices on the market are less able to deliver nicotine? Or is it that these experienced e-cig users have learned the technique required to absorb nicotine from an e-cig, that na?ve users in prior studies were unable to do? Maybe it is a combination of both factors?
Some may be concerned that e-cigs are capable of delivering meaningful amounts of nicotine relatively quickly, but to me this raises the possibility (as many users have already claimed) that these devices may really help smokers to quit. Tomorrow I will report on additional studies (including those on e-cigs) with promising (and some not-so-promising) findings.
As one who has been tobacco free for almost 2 years after smoking for 30 years and used a PV (personal vaporizer -e-cig) to make that transition, I can say from experience there is a significant difference in different PV models as well as user experience. The widely marketed devices such as "Blu" and Smoke Everywhere are generally the "bottom-feeders" of the industry and perform quite inconsistently and overall quite poorly.
There is a definite "learning curve" with using PV's. There are also around 100 different PV variations as well as about 8 different nicotine strength e-liquids to choose from ranging from 0mg to 36mg. New users really need a resource to "wade" through all the options. The Electronic Cigarette Forum (ECF) is a good resource but one that requires a good amount of reading and asking questions. I read ECF for two weeks before I ordered my first PV. The people on ECF (just average "joes" like all of us) are a wonderful support community.
Many of us veteran "vapers" have a basic understanding on a PV's effectiveness that the Rule of Thumb is: the more it looks like the real thing, the worse the performance. Although every user has different needs to a point, in general, the devices with larger/better batteries that are manual (small button) perform better and more consistently than the small, auto batteries like Blu. I good starter PV would be an eGo or Riva 510 device. As a comparison point, the Blu has an 80mAh battery, where as the eGo has a 650 mAh battery. Big difference in performance, consistency and effectiveness. Plus the better devices such as the eGo 510 usually cost LESS than the highly marketed devices. For a new person trying to transition away from cigarettes, it generally requires starting out with a nicotine level in the e-liquid of 18mg to 24mg. All these differences need to be considered in studing the effectiveness of vaping as an alternative to tobacco.
Any way, I hope you keep your mind "open" on this device that saved my life and do more study and research.
Smoke-free since 3/27/2009. No more wheezing, no more morning cough. Smoked for 45 years. Quit and relapsed too many times to count. Now, no urges whatsoever to go back to smoking.
My initial motivation to buy this product was monetary more than health. I have tried to quit too many times to count, but the horrible truth is I enjoyed smoking! Spending $8.28 a day for a pack of cigarettes was hard to justify with my daughter going off to college. Deep down inside I didn't want to quit, and I had even bargained with myself - I wouldn't really quit, I would just stop for 30 years, and on my 80th birthday, I'd start again. It may sound ridiculous but I really had that thought embedded in my brain, I just couldn't make the first move to quit. I was jealous of what I considered to be "social smokers" who could smoke on weekends while out with friends, and then go smoke free for days. That was just not me. Regardless of the NRT I tried, when I saw someone light a cigarette, the smell of the smoke, the thought of inhaling that smoke, was so enticing that my willpower threw up it's hands and gave up.
So what happened? How did I go from loving smoking to finding it disgusting? What caused that wonderful smell of cigarette smoke to become vile? Why can I now comfortably go hours without vaping, when I HAD to have a cigarette every two hours? I had no withdrawal symptoms, because I still use nicotine. I would suck down two cigarettes on a break, now I use my PV once or twice and I'm good for a few more hours.
Turns out my desire for nicotine is being satiated, the relaxing sensation of exhaling the stress out of me is still there, and I'm able to accomplish this without the harmful effects of tobacco smoke. I am so grateful that this product exists. Finally, we have a better alternative.
It really is a product that can save lives, and I feel strongly enough about this that I will continue to advocate for this product to remain available to current adult smokers.
Thank you for the opportunity to voice my experience.
(And thanks to wv2win & vocalek)
The above article states that they used 16 smokers. I assume from that the test subjects had no idea on how to vape or use an E cigarette. As sated above the equipment makes a difference but just as important is how you puff on a vaping device. Smokers tend to take quicker puffs than vapers do. This is because there is a limited amount instantaneous of power that can be delivered by the battery to the coil. This is especially true with smaller batteries. They just can't deliver the energy that quickly and so don't have the power to vaporize the liquid. So vapors tend to take longer slower puffs the get to the same amount of nicotine and smoke as they would from a cigarette. They may also vape more than they were smoking. This isn't just a matter of going to the store and picking up a pack of cigarettes or even an E cigarette at your local convenience store. In fact that just about the last place you would want to go.
OR, perhaps, its because Eissenberg's first study was flawed. His research model was at fault. Not the electronic cigarettes.
Here is a post from Eissenberg 02-21-2010:
http://www.e-cigarette-forum.com/forum/medical-research/69409-cnn-com-today-eissenberg-study-feedback-69.html
>>I used it last night (18 mg cartomizer) and tested my urine with Nicalert strips this morning. Result? 5/6. Clearly, this result is consistent with recent nicotine exposure. <<
Yet this is what is put out in the media:
http://www.consumeraffairs.com/news04/2010/02/ecigs_evaluation.html
>>In terms of nicotine delivery, these products were as effective as puffing from an unlit cigarette."<<
His first study shows little to no absorbtion. At his home he gets a different result. But you didn't read about that in the media. Instead of his study being at fault. He still chose to blame the product.
Wonder how many people decided NOT to try using an electronic cigarette based off his original study?
I bought my first e-cig with NO intention of quitting (and I have smoked for 40 years) I bought it to use in my new car because I didn't want to stink it up by smoking in it. I was completely surprised when I realized that within two or three days of using the e-cig I had NO desire to smoke cigarettes. I had no withdrawl, no craving, nothing.
I am closing in on two months of no cigarettes now and my health is demonstrably better and I have saved money too. The cancer society should distribute e-cigs to smokers if they REALLY want to get people off of cigarettes because it is the one thing that actually works! I will decrease the nicotine level in the liquid that I use over time, but I'm not going to do so drastically because I don't want to 'tempt fate' and end up going back to smoking.
Noone is failing to recognize drug seeking behavior. Many of us are simply recognizing that seeking a drug that generally doesnt kill you (e.g. caffeine in coffee, or nicotine in a nicotine replacement medicine) is of much less concern than drug seeking when that drug comes along with thousands of dangerous chemicals proven to cause premature death (as in cigarettes) or along with other dangers (e.g. risk of contracting HIV when seeking a drug via a shared syringe).
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