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retinitis pigmantosa & moya moya syndrome
mrstreklady posted:
DR. I read some where that retinitis pigmantosa(my dad had this) can cause birth defects such as hearing loss & moya moya syndrome is that true?

my dad aslo had alzeimers & parkinson@ the same time my question is: what the percentage of risk like 10% or a 50% chance that i can devolp one or both eather parkinson or alzeimer when i get in my late 60s early 70s there is a family history of this on my dads side of the dad was the only one to have both of these deasese.
Richard C Senelick, MD responded:
I am sure you are aware that retinitis pigmentosa (RP) is a hereditary disease, but your chances of getting it varies greatly depending on which gene, if any, you inherited. That particular question is best answered by an opthalmologist.

I don't know of any relationship between RP and Alzheimer's Disease ( AZ) or Parkinson's Disease (PD). Both AZ and PD have a genetic component. It is only a minimal factor in PD, but is a greater factor in AZ. People who have a parent, brother, sister or child with AZ are more likely to develop the disease. I don't belive we know the exact figure, but is certainly less than 50%.

Age itself is the greatest risk factor for AZ. The risk of developing AZ doubles after age 65 years and after the age of 85 about 50% of people will have AZ.

There are some things you can do to help prevent AZ.
  • Control and limit your alcohol intake
  • Stay physically active
  • Keep your mind engaged with cognitive activities and social interaction

Good Luck
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