Skip to content


    Exciting News for WebMD Members!

    We've been busy behind the scenes building new message boards for you. You'll have new and easier ways to find messages, connect with others, and share your stories.

    And, this will all be available on your smartphone or other mobile device!

    What Do You Need to Do?

    The message board you're used to will be closing in the coming weeks. While many of your boards will be making the move to our new home, your posts will not. Want to keep a discussion going? Save posts you want to continue (this includes your member profile story), so that you can re-post them in the new message boards.

    Keep an eye here and on your email inbox, we'll be back in touch soon to give you all the information you need!

    Yours in health,
    WebMD Message Boards Management

    Includes Expert Content
    Legal marijuana?
    nannysgrl posted:
    What is this stuff they call legal marijuana? Have seen some detrimental actions by one of my sons. I know he is a big proponent of the 'real stuff' but he is also into something i believe they call K2. would like any info that can help me understand why the big personality change in him.
    Betty Ford Center
    James Golden, MD responded:
    K-2, or spice, is marketed as an herbal substance. It can either be used as incense or smoked, and it remains legal in the United States. The product contains synthetic compounds (psychoactive substances) similar to THC. The psychoactive substances in K-2 bind very strongly to the CB-1 receptors in the brain but not so strongly to the CB-2 receptors, resulting in very accuentuated psychoactive effects. If a person would use this substance on a regular basis, then cumulative effects on the CB-l brain receptors could explain a personality change.

    So far, serious drug reactions such as seratonin syndrome have not been reported, but K-2 abuse is on the rise.

    Featuring Experts from Betty Ford Center

    Harry L. Haroutunian, MD., is an internationally known speaker on the topics of Addictive Disease and its treatment. He is Board Certified in Family M...More

    Helpful Tips

    Will smoking weed effect my everyday life and health due to my age?
    I'm 14 and I've been smoking marijuana since I was 12 due to family problems&a family loss and my grades seem to me slowly going down ... More
    Was this Helpful?
    1 of 1 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.