Skip to content
Includes Expert Content
Legal marijuana?
avatar
nannysgrl posted:
What is this stuff they call legal marijuana? Have seen some detrimental actions by one of my sons. I know he is a big proponent of the 'real stuff' but he is also into something i believe they call K2. would like any info that can help me understand why the big personality change in him.
Reply
 
avatar
Betty Ford Center
James Golden, MD responded:
K-2, or spice, is marketed as an herbal substance. It can either be used as incense or smoked, and it remains legal in the United States. The product contains synthetic compounds (psychoactive substances) similar to THC. The psychoactive substances in K-2 bind very strongly to the CB-1 receptors in the brain but not so strongly to the CB-2 receptors, resulting in very accuentuated psychoactive effects. If a person would use this substance on a regular basis, then cumulative effects on the CB-l brain receptors could explain a personality change.

So far, serious drug reactions such as seratonin syndrome have not been reported, but K-2 abuse is on the rise.


Featuring Experts from Betty Ford Center

Betty Ford Center Board of Directors member A. Thomas McLellan, Ph.D ., Professor, Department of Psychiatry and Director, Penn Center for Substan...More

Helpful Tips

FOR FAMILY & FRIENDS OF ADDICTED - SEE 'NARANON'
FOR ANYONE DEALING WITH A RELATIVE OR FRIEND SUFFERING WITH ADDICTION - SEE "NARANON" THERE ARE SUPPORT MEETINGS IN THIS AREA ALMOST ... More
Was this Helpful?
2 of 3 found this helpful

Related News

There was an error with this newsfeed

Related Drug Reviews

  • Drug Name User Reviews

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.