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medication assisted treatment for opiate addiction
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lunaoneluv posted:
Hello i was wondering if anyone has any advice on the safest medication to use in treatment for opiate addiction in a patient that has severe liver cirrhosis. Methadone is not an option.
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Betty Ford Center
Anthony Tornay, MD responded:
This would depend on how do you define treatment.

If you mean long-term maintenance (substitution), then methadone is the safest choice.

Buprenorphine has been associated with liver injury (mechanism unkown) and should be used with caution if long-term.

If treatment means abstinence with initial detox, our standard protocols are Buprenorphine, Clonidine and sedatives - again, used with caution.


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