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Symptoms:
dull, usually mild, but near-constant stinging sensation felt in urethra or penis tip
often is worse before and/or after urinating, but sometimes seemingly not related to urination
occasional random twinges of pain or discomfort in the urethra
polyuria
very mild dysuria
no visual signs, except slight puffiness of meatus just after urination
generalized pruritus, mostly trunk and neck
these symptoms have lasted for 5 months - they were worst shortly after onset, tapered, but have seemingly reached a "plateau" where it doesn't seem to be getting any better overall - it just waxes and wanes
Workup thus far:
gon & chlam tested shortly after onset, both neg.
Cipro 14 day course given shortly after onset, little or no change to symptoms.
full STD panel (including gon & chlam again) 45 days after onset, all neg.
standard blood panel, including blood sugar, liver and kidney function, all normal (GP says "excellent").
Bladder-kidney ultrasound reveals nothing.
Cystoscopy reveals nothing in bladder, "possibly a little irritation" in urethra, doxycycline 7 day course given afterwards, no change to symptoms.
Several urinalyses were performed at urologist, some with attempted culture of bacteria, none ever detected bacteria or WBC. Those performed shortly after onset indicated microhematuria which persisted for a couple of months, while the recent ones ones have not had hematuria. Urine pH has been "on the acidic side" (pH of 5).
Azithromycin 5-day course given for an unrelated issue - this produces temporary relief of urethral issues.
Two digital rectal exams, one shortly after onset, the other months later, both revealed nothing
Urologist has noted that the urethra is very sensitive to contact, based on the fact that the cystoscopy caused excrutiating pain in urethra despite numbing gel. Also, manual examinations of the urethra by urologist have been more painful than he would have expected.
No discharge, odor, or lesions were ever observed.
So the only actual clinical findings were:
microhematuria which is now gone
urethra sensitive to contact
urethra "may have had a little irritation" (uro's words)
So I'm at my wit's end. My uro is a nice guy but it seems that he is out of ideas and is now toying with garbage diagnoses such as interstitial cystitis. Any suggestions would be greatly appreciated. I'm thinking that it must be some sub-clinical infection or resistant strain of bacteria, and considering trying d-mannose or a different antibiotic.
You can follow a standard allergy elimination protocol (fabrics, cleansers, foods). And you can get checked for parasites, especially if you have eaten shellfish (like fried clam strips or something) near the beginning of these symptoms, that would make me even more suspicious of parasite over allergy.
Allergies are more common, whether to a detergent, fabric softener, soap, fabric, lotion, food, etc. Even a mild nut allergy can cause irritation of the skin in the same places mentioned above.
It's only a urology issue because your penis is involved, but the cause of your symptoms may not be urologic at all.
Candida cannot be treated with an antibiotic. It is a fungus, and has to do with a lowered immune response (which could be an after-effect of the strong antibiotics), and poor diet (too much sugar and red meat, not enough water and fiber).
There are two critical steps in treating a urinary tract infection. The first one is a urinalysis to determine you actually have an infection, and then a sensitivity test of the bacteria found in the urine sent for analysis to determine which antibiotic will be effective. It sounds like some idiot didn't do the second step, otherwise your first antibiotic treatment should have been successful since they would have known in advance which antibiotic to prescribe.
Diverticulitis is very serious, but not a urology issue. It may however have influenced your candida problem.
Since you had some very powerful antibiotics that killed all the good flora in your gut, you need to be taking a good probiotic for at least a month to restore that intestinal flora. Restoring your good flora will dramatically help to control the candida.
Cranberry can only prevent e.coli bacteria from adhering to the bladder lining. It cannot treat an infection that has already occurred. Most UTIs are e.coli based, but some are not, and that's what's important about your urinalysis and learning what treatment will be effective.
Your family doctor is completely incapable of dealing with genito-urinary issues. A GP gets about as much training in that area as you do in rocket science. Fortunately you went to see a urologist later.
It's not clear from your note what symptoms are persisting, and why your urologist would be dismissive. It's your job to prompt him to solve the problem or provide concrete answers.
The mouth ulcers are again from the weakened immune system from the horrible antibiotics you took. You need medical treatment to control the candida right now until you can restore your own immune system. It may be a prescription mouthwash as well as an anti-fungal medicine. Sorry that one thing lead to another.
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