I began experiencing what I thought was a UTI 4 weeks ago. I noticed that I was needing to urinate much more frequently than usual. I had experienced this before during previous pregnancies and would be prescribed antibiotics which would immediately alleviate the symptoms and clear the infection. I called my doctor who prescribed amoxicillin -- I will admit that I did not consistently take the antibiotic although I did eventually finish the cycle. The infection appeared to have cleared only to return with a vengeance just a few days later. I called my general practitioner, explained my symptoms which included the very urgent need to urinate frequently, the feeling of a full bladder even after urinating and the need to urinate even more frequently at night. He prescribed Macrobid for 5 days. The symptoms persisted. I called my doctor once more and he had me go in for a visit. My urinalysis was negative but he ordered a urine culture. After 48 hours, my culture yielded abnormal levels of nitrites, leukocytes and a slightly elevated level of protein in the urine. The doctor then prescribed Levaquin (500mg twice per day). After 5 days of taking the Levaquin, I still had no relief and began to exhibit symptoms of an adverse reaction to it, including hallucinations, pain in the tendons and muscles and depression. I went back to the doctor, explained the situation and he told me to discontinue the use of the antibiotic. He conducted yet another urinalysis which came back negative and a urine culture -- results are still pending. I am still very uncomfortable, and my only symptoms are the persistent feeling of a full bladder even after urinating, the need to urinate frequently, especially at night. I have no pain in my back, no fever, no chills. I also had an ultrasound done -- I had free fluid in the cul de sac, some fluid in the endometrial lining and a slight thickening of the bladder lining. The doctor said this didn't indicate anything. He did mention the possibility of interstitial cystitis. Any ideas or suggestions?