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    Dr.G, any thoughts and suggestions?
    gui_66 posted:
    Hi Doctor. I am Bipolar II and i take Lithium 675 mg with 0.5 in blood; Lamictal 200 mg; Aripiprazole 2.5 mg; and Clonazepam 3 mg. Not too? For me causes daytime sleep and wake often at night. It is worthwhile that the Aripiprazole akathisia caused me so much I have to take clonazepam? Aripiprazole makes some effect in such low doses? Because I got to the depressive phase. The dream will be for much medication? Aripiprazole is the other? How to be good in the depressive phase? Thanks.
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    Joseph F Goldberg, MD responded:
    Dear gui_66,
    Aripiprazole hasn't been shown to treat depression in bipolar disorder (the two large studies of both found it was no different from placebo). You might ask your doctor about switching it to either Seroquel or Latuda, both of which have data (and FDA approval) in bipolar depression.
    Dr. G.

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