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    Dr.G, any thoughts and suggestions?
    gui_66 posted:
    Dr.G and increasing lamotrina 300 mg or 400 mg not achieve control bipolar depression? Because Seroquel makes me sleepy and do not know how to react Latuda. Thanks.
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    Joseph F Goldberg, MD responded:
    Deaf gui_66,
    One could experimentally try increasing lamotrigine to 300-400 mg/day but keep in mind the studies of lamotrigine for bipolar depression all showed it was the same as placebo. Its utility is more for prevention of depression than here-and-now depression. The other treatments I mention are more evidence-based.
    Dr. G.

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