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    Statin wars: Doctors are bitterly divided over calls for half of all adults to be put on pills to cut cholesterol.
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    surfoahu posted:
    This was published one year ago. Very good. Notice the comments at the end of the article. Public attitude towards statins is changing.

    http://www.dailymail.co.uk/health/article-2700573/Statin-wars-Doctors-bitterly-divided-calls-half-adults-pills-cut-cholesterol-Heres-need-know.html#comments
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    iride6606 responded:
    Now the other side of the argument also published a year ago. The problem with your link is that it's a feel good article for the anti-statin crowd made up mostly of sales managers. There is no science behind it, just using the personal experiences of a few and trying to apply that to the masses, doesn't work that way.


    When you look at a real study based on 150,000 participants over 5 years the science is undeniable.


    Not only have the dangers of statins been greatly exaggerated, according to a huge meta-analysis in the British Medical Journal, but there may also be benefits to the drugs other than their ability to lower cholesterol.
    Researchers at the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease looked at 20 studies published from November 1994 to March 2014 (http://www.bmj.com/content/349/bmj.g3743). For about five years, the studies tracked 150,000 middle-aged and older men and women who took statins.


    "Although early concerns about statin-induced hepatotoxicity and cancer have subsided owing to reassuring evidence, two of the most common concerns that clinicians have are myopathy and diabetes," the study states.


    But those risks are actually minimal. "The increased risk of diabetes associated with statins seems to be confined mainly to people who are already at high risk of diabetes," the study says. "Furthermore, all of the incident diabetes events occurred in patients who had at least one risk factor for diabetes: impaired fasting glucose, body mass index greater than 30, metabolic syndrome, or glycated hemoglobin greater than 6%."


    Regarding muscle aches, researchers cite one study in which "27% of patients whose statin was discontinued had a documented muscle-related side effect, yet nearly all of these patients were able to tolerate a re-challenge. The fact that symptoms often do not recur on re-challenge suggests that they are unrelated to the statin."


    Note the last paragraph, of the 27% that stop due to muscle related side effects have almost no reoccurrence when the restart placing the cause attributed to statins in doubt. Just more hype by the anti statins sales managers.


    http://www.managedcaremag.com/archives/2014/9/meta-analysis-backs-statin-use


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    Statin use is generally safe, and NOT associated with cancer and myopathy
    This network meta-analysis study provides evidence on the comparative tolerability and harms of individual statins. Overall, statins as a ... More
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