Skip to content


    Attention All WebMD Community Members:

    These message boards are closed to posting. Please head on over to our new WebMD Message Boards to check out and participate in the great conversations taking place:

    Your new WebMD Message Boards are now open!

    Making the move is as easy as 1-2-3.

    1. Head over to this page:

    2. Choose the tag from the drop-down menu that clicks most with you (and add it to any posts you create so others can easily find and sort through posts)

    3. Start posting

    Have questions? Email us anytime at [email protected]

    100% Relief for me
    carlwilliams254 posted:
    I've been free of these terrible headaches for years now. Ever since taking an SSRI (serotonin reputable inhibitor)' specifically Sertraline HCL, a drug normally prescribed for anxiety/depression.

    It's pretty benign in that it simply maintains a higher concentration of serotonin and clinical studies seem to support it's beneficial effects . (sorry no references).

    So for me, no clusters in all the years I've been taking it. I find it a great alternative to Imitrex, which also works wonders but it's pretty heavy-duty!!!!!

    Cheers to all.
    Was this Helpful?
    1 of 1 found this helpful
    An_252454 responded:
    I agree about the serotonin factor. I've found that taking amitriptyline got me over my first bout (20mg night) and it took about 2 months to begin to work after several months of a chronic headache and nerve pain and swelling (None of the other treatments worked for me (nerve blocks, botox injections--I tried a lot.) I've had to continue on the Amitriptyline medication for 5 years although I hate the weight gain with this drug. If I try to go off this Rx, the headaches come back. I was headache free with the cluster-type one-sided headache for 5 years (excluding the occasional migraines that lasted a day treated with Imitrex) until I got another bout 2 months ago--scary with terrible one-sided head pain everyday. To combat this monster, I added 3 mg of melatonin at night along with my amitriptyline, made sure I got plenty of sleep, added vitamin D3, higher dose b12 lozenges with methylcobalamin, and when my head was hot like a poker, used natural capsaicin cream on the top my head and rubbed a tiny bit on the inside of my nose on the side of my head that hurt. I can never drink alcohol during these bouts. I gradually got better, and as of today, cross my fingers, am pain free with the cluster-type headache, and now know what to try if it strikes again. If any of this information can benefit just one person, it is worth writing, as this is a horrible condition.
    Good luck to all sufferers!

    Spotlight: Member Stories

    I've been dealing with cluster headaches for over fifty consecutive days. Each day has been a struggle either against people who don't believe...More

    Helpful Tips

    Getting rid of cluster headaches
    You guys try 500mg magnesium pill when u get up and 500mg magnesium at night be4 bed with a 5 mg melatonin at night.. Try not to smoke or ... More
    Was this Helpful?
    1 of 1 found this helpful

    Helpful Resources

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.