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    WORRIED09 posted:
    :confused: Folks I am confused right now. My wife and I are approximately 18 to 20 weeks along in the pregnancy and our first blood test and unltra sound (with perintologist at approximately 14 wks-told us it was a boy)all came back negative up too this point inthe pregnancy. This last set of blood test though had a above normal AFP result now how can this change. My wife is 39 and I am 40 but all our blood test came back fine when we checked to make sure we could even have childern. Please help this confuse and worried husband. to understand. Worried
    _Paula responded:
    I would not worry- especially if your 14 week u/s looked fine- all the AFP does is give you the risks- or ratio- my last AFP came back high- and gave me a 1:300 risk of Downs- well I thought my risk was higher than that based on my age alone- I have a level II u/s done and my DD is fine. These tests can cause unnecessary worry.
    FCL responded:
    Also, the tests done during pregnancy bear no relation to the tests you had done before. The AFP checks for a substance produced by the baby's liver. Also, as things like Down Syndrome are pretty much random occurrences, it's unlikely to see that show up either in pre-pregnancy blood tests (also because these tests seldom look for it).

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