Skip to content


    Attention All WebMD Community Members:

    These message boards are closed to posting. Please head on over to our new WebMD Message Boards to check out and participate in the great conversations taking place:

    Your new WebMD Message Boards are now open!

    Making the move is as easy as 1-2-3.

    1. Head over to this page:

    2. Choose the tag from the drop-down menu that clicks most with you (and add it to any posts you create so others can easily find and sort through posts)

    3. Start posting

    Have questions? Email us anytime at [email protected]

    Includes Expert Content
    Ovulation and LH Surges
    brandi2022 posted:

    I have an ovulation question. I got a positive OPK yesterday when I tested at 1:30PM. Then I got a negative test at 6:30PM that same day. Today, I got another positive test at 1:30pm. I held my urine for 2-3 hours on each test, so I don't think one was diluted. I know that surges can last a day or two, but I don't know why I would have a positive, then go to negative, then have another positive. Thanks for any anwers.
    David K Walmer, MD, PhD responded:
    Dear brandi2022, Our goal is to figure out if your positive tests represent a real LH surge or not. Occasionally a woman will have a false positive test. Explanation: Women with ovulation problems sometimes have naturally high levels of LH in their blood stream that can result in a weak false positive OPK test. Those tests can alternatively be positive and negative. Alternatively, the test in the middle could have been a false negative test. There may have been something wrong with the one test that was negative. If you had a real LH surge then the hormone wouldn't really appear, disappear and reappear. We can figure this out by checking a serum progesterone one week after you had the surge and waiting to see when you get your next period. A real LH surge is followed by a rise in progesterone and the next period should appear about 14 days later if this is a normal LH surge. If the test was a false positive then your progesterone level will remain low. Here's hoping that it was the former and that your progesterone level is high but you miss your period because you are pregnant. Good luck!

    Helpful Tips

    TTC Basics you need to know
    Ask yourself the following questions: What steps are you using to concieve?? Are your cycles regular? How long have you actively been ... More
    Was this Helpful?
    6 of 6 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    For more information, visit the Duke Fertility Center