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    Week #2 fatigue tip Are your medications causing fatigue?
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    Scott Zashin, MD posted:
    Many medications are associated witih fatigue. For the RA patient, methotrexate has been assoicated with this problem.In my patients who note fatigue, possibly from MTX, in addition to daily folic acid, I also add Folinic Acid (leukovorin) which is taken once weekly 8-12 hours after MTX. This prescription drug has rarely been associated with allergic reactions. I find that leukovoirn may also help other side effects in addtion to fatigue that can occur with MTX incudling mouth sores, hair loss and low white blood counts without decreasing efficacy if taken in the time frame recommended.
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