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    Itchy blisters erupting on hands or feet only
    squiddley posted:
    I am hoping against hope that someone will see this and think "oh I know what that is" because I have about given up ever knowing. Nothing works for long except for heavy use of antihistamines which is getting old. But then so am I.

    For about 15 years I have had a chronic problem with intense itching in very localized spots on my hands (less commonly on the feet) that becomes so unbearable I could scream. Scratching doesn't help much because the source seems to be pretty deep under the skin. Originally, tiny little blisters would appear in clusters, and the itching would fade. The last few years, though, the blisters have become bigger and keep recurring in the same spots over and over. I take generic prescription hydroxyzine 20mg a day which helps most of the time. If I ever run low or miss a dose the blisters come roaring back. My doctors/dermatologist are pretty much indifferent to it. But if you have ever awakened at night itching so intensely you want to chop your hand off just to make it stop you'd understand. One doctor told me "well, maybe you'll just have to get used to waking up wanting to chop your hand off." They say don't break the blisters but is the only way to stop the itch. But then it scabs over, heals, and comes back.

    I have a preference for finding a cause and treating a problem rather than just covering up symptoms. Does this ring a bell for anyone? I have had hundreds of allergy tests (nothing higher than 2) and excema/psoriasis treatments have no effect.

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